Curcuminoid-loaded poly(methyl methacrylate) nanoparticles for cancer therapy

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Curcuminoid-loaded poly(methyl methacrylate) nanoparticles for cancer therapy

Curcuminoids (Curs), oleoresins from Curcuma longa L., have known anticarcinogenic and anti-inflammatory properties, but high toxicity, poor aqueous solubility and susceptibility to degradation in body fluids are deterrents to their clinical administration. Poly(methyl methacrylate) nanoparticles (PMMA-NPs) are biocompatible and resilient and can entrap hydrophobic drugs. The present investigat...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2018

ISSN: 1178-2013

DOI: 10.2147/ijn.s124021